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Descaling solution according to KRISTENSEN

Kristensen decalcifying solution is widely used in medical diagnostics and research, especially in histology for the preparation of bone and dental samples. It contains formic acid (HCOOH), an efficient decalcifying agent, and sodium formate (HCOONa) for pH stabilization, while water serves as the solvent base. The formic acid chelates calcium ions from the tissue, dissolving them and making the tissue softer and accessible for sectioning and staining. Sodium formate helps to regulate pH during the process, ensuring gentle decalcification and preserving tissue structure.

On a molecular level, these chemical interactions enable efficient removal of calcium salts from hard tissue without compromising critical morphological details. The use of this specific combination in histology leads to precise, clear histological results. These allow for more accurate diagnostics and research, especially when examining bone tissue or teeth, where preservation of microscopic structure is critical.

Article no.: 12562

Decalcification of tissue samples

  •   Container size and order number Net price Amount
    Descaling solution according to KRISTENSEN - 250 ml
    Order number: 12562.00250
    29,60 €
    Descaling solution according to KRISTENSEN - 500 ml
    Order number: 12562.00500
    58,60 €
    Descaling solution according to KRISTENSEN - 1.000 ml
    Order number: 12562.01000
    76,40 €
    Descaling solution according to KRISTENSEN - 2.500 ml
    Order number: 12562.02500
    160,40 €
    Descaling solution according to KRISTENSEN - 100 ml
    Order number: 12562.00100
    19,60 €
    Descaling solution according to KRISTENSEN - 5.000 ml
    Order number: 12562.05000
    229,80 €
    Descaling solution according to KRISTENSEN - 10.000 ml
    Order number: 12562.10000
    Preis a.A.

Important Information

UN-Nummer: 3412

Warning labels:

Lagerung: 15 … 25 °C

Haltbarkeit: 48 Monate

safety data sheet

product information

Relevant Incredients:
• Formic acid

Technical informations

specifications

Instructions / Protocol / Recommendations

Verwendung:

The Kristensen decalcification solution is used in in-vitro diagnostics to prepare bone and tooth samples for histological analysis. Its main purpose is to enable the decalcification of tissue samples and thus simplify their preparation for microscopic examinations. It binds and removes calcium ions from the hard tissue, making it soft and accessible for tissue sections. At the same time, it stabilizes the pH value during the decalcification process, which preserves the tissue structure and enables precise, clear histological diagnostics. The specific combination of ingredients enables the preservation of critical morphological details, which is of great importance for the accuracy of histological research.

Prinzip:

This descaling solution consists of formic acid, sodium formate and water, which together act as an effective means of binding and removing calcium from tissue or cell structures. Formic acid, a weak acid, helps to remove calcium ions and convert them into a soluble form. Sodium formate acts as a stabilizer by neutralizing the acid and protecting cell structures from excessive degradation. These properties make the solution ideal for in-vitro diagnostic applications as it enables effective and gentle removal of calcium from tissue samples.

Verfahren:

This descaling solution consists of formic acid, sodium formate and water, which together act as an effective means of binding and removing calcium from tissue or cell structures. Formic acid, a weak acid, helps to remove calcium ions and convert them into a soluble form. Sodium formate acts as a stabilizer by neutralizing the acid and protecting cell structures from excessive degradation. These properties make the solution ideal for in-vitro diagnostic applications as it enables effective and gentle removal of calcium from tissue samples.

Hazard and safety instructions

Signal Word 1: Gefahr
Signal Word 2: acid_red, exclam, ,
Warning labels: