Congo Red in PBS for Fungi Detection
In solution, Congo red is stabilized by the azo group (-N=N-) and the sulfonate groups on the naphthalene rings, giving the dye a negative charge and increasing its solubility in water.
Congo red solution in PBS is used in medical diagnostics to identify fungi. Congo red specifically binds to the cell walls of fungi, allowing them to be visualized under the microscope and distinguished from other cell types. The application of this solution is particularly valuable in disease diagnostics for the identification of fungal infections.
Article no.: 12118
Staining of tissue samples
product information
Relevant Ingredients:
• PBS buffer, pH 7.4 - 10x concentrate
• Congo red (C.I.: 22120)
Instructions / Protocol / Recommendations
Verwendung:
Congo Red in PBS Staining Solution for Fungal Detection is used in in vitro diagnostics to visualize fungi in tissue samples. The specific binding of Congo Red to fungal cell walls allows them to be detected under the microscope and distinguished from other cell types. This is particularly important for the diagnosis of fungal infections in medical examinations.
Prinzip:
Congo Red is an azo dye-based anionic colorant used in in vitro diagnostics for the identification of fungal structures. It is used in PBS (buffer solution) with a pH of 7.4 to ensure that the dye retains its biological activity during the assay. Dye binding occurs through non-specific electrostatic interactions between the positively charged sites of the dye and the negatively charged cell wall components of the fungi, such as chitin and glucan. When used in in vitro diagnostics, Congo Red in PBS enables rapid and easy identification of fungi in test materials such as tissue or smear samples.
Verfahren:
Congo Red is an azo dye-based anionic colorant used in in vitro diagnostics for the identification of fungal structures. It is used in PBS (buffer solution) with a pH of 7.4 to ensure that the dye retains its biological activity during the assay. Dye binding occurs through non-specific electrostatic interactions between the positively charged sites of the dye and the negatively charged cell wall components of the fungi, such as chitin and glucan. When used in in vitro diagnostics, Congo Red in PBS enables rapid and easy identification of fungi in test materials such as tissue or smear samples.