Potassium Citrate Fixation-Buffer pH 7.0

The potassium citrate fixation buffer pH 7.0 is an aqueous solution and contains potassium citrate buffer, magnesium sulfate heptahydrate and N-ethylmaleimide. This fixation buffer is primarily used for the preservation of cellular structures and biomolecules during cell and tissue fixation in cell biology and histology.

The buffer ensures a stable pH environment through potassium citrate buffer, while magnesium sulfate heptahydrate regulates ionic strength and stabilizes protein structures. N-ethylmaleimide, a thiol-reactive reagent, selectively modifies cysteine residues in proteins and prevents nonspecific interactions during fixation.

Thanks to effectively preserving cellular and tissue structures and maintaining the integrity of proteins and other biomolecules, potassium citrate fixation buffer is suitable for reliable and precise analyses in various cell biology and histology applications.